Nalane ea khale ea li-capsules, Glatatin e lula e le thepa ea mantlha ea capsule ea mantlha ka lebaka la mehloli ea eona e mengata, 'me e sebetsa hantle. Ka keketseho ea khetho ea batho bakeng sa li-capsules, li-capsules li sebelisoa haholo masimong a lijo, lihlahisoa tsa meriana le tsa tlhokomelo ea tlhokomelo ea bophelo bo botle.
Leha ho le joalo, ho hlaha le ho phatlalatsoa ha lefu la COW le bokuli ba leoto le molomo le molomo li hlahisitse mathata ka lihlahisoa tse nkiloeng ke liphoofolo. Lisebelisoa tse sebelisoang haholo bakeng sa Glatin ke masapo le matlalo a koluoa, 'me ho likotsi tsa eona ho hoheletse batho haholo. Bakeng sa ho fokotsa kotsi ea polokeho ea lisebelisoa tsa "catPule tse se nang letho indastering, litsebi tsa khoebo li tsoela pele ho etsa lipatlisiso le ho ntlafatsa thepa e loketseng ea semela.
Ntle le moo, li-capsules tse fapaneng li eketseha, mefuta-futa ea litaba tsa eona e lemoha hore li-capsules tse amanang le li-conts e ikhethang li na le mathata a ba bang ka thepa e ikhethang. Ka mohlala, litaba tse nang le lihlopha tsa ADEHYD kapa ho nka khato ho etsa lihlopha tsa Addehde ka tlas'a maemo a itseng li ka lebisa ho crosern; Likahare tsa ho fokotsa haholo Marillard li ka arajoard (Malard Rection) le Boikemisetso ba Gelatin); Litaba tse hygroscopic li tla etsa hore khetla ea capsule ea Gelatin e lahleheloe ke metsi 'me e felelehe ho ba thata. Mathata a botsitso a boletsoeng ka holimo a Gletan Hollow Capsules a khahliloe haholo ho nts'etsopele ea thepa e ncha e ncha ea capsule
Ho entsoe boiteko bo bongata. Palo ea Konopo ea Machaena 200810061238.x e ile ea etsa kopo ea ts'ebeliso ea sodium celbalane e le ntho e ka sehloohong ea capleule ea mantlha; 200510013285.Ba kopo ea tšebeliso ea starch kapa starch comppecipition e le thepa e ka sehloohong ea capleule ea mantlha; Wang GM [1] ho tlaleha moralo oa Chitosan Capsole Xiaoju Zhang et [2] e tlaleha hore protheine ea soybean ke eona ntho e ka sehloohong ea capleule ea sehlooho. Ehlile, tse ithutoang haholo ke lisebelisoa tsa khomphutha. Har'a bona, li-capsules tse nang le marulelo tse entsoeng ka hydroxypropyproppyl methyl cellulolose (HPMC) e hlahisitsoe.
HPMC e sebelisoa haholo lebaleng la lijo le meriana, 'me ho sebelisoa khafetsa meriana ea meriana e tlalehiloeng meriana ea linaha tse fapaneng; FDA le Europe Union Union e amohetse HPMC e le tlatsetso ea lijo tse tobileng kapa e sa tobang; Gras e tlalehoa e le ntho e sireletsehileng, Che. Gorn 000213; e kenyellelitsoe ho dacfasase ea Jecfa, in No.464, ha e felle tekanyetso e phahameng ea letsatsi le letsatsi ea Hpmc; Ka 1997, Lefapha la Bophelo ba China le ile la e amohela e le lijo tse eketsang lijo le thickener (No. 20), ho latela tlhahiso e hloka ho kenyelletsa [2-9]. Ka lebaka la phapang ea phapanyetsano ea thepa le Gelatin, lengolo la li-capsules tse se nang letho le thata haholo, 'me mahlahahlaha a mang a tlokotsi a hloka ho eketsoa, joalo ka Akacia, grimad ea likoloi), starch, jj.
HPMC Hollow Capsule ke sehlahisoa se nang le mohopolo oa tlhaho. Lintho tsa lona tsa boitsebiso le lihlahisoa li amoheloa ke Bolumeli ba Bolumeli, Boislamo le Mekhatlo ea limela. E ka khotsofatsa litlhoko tsa batho ba nang le malumeli a fapaneng le mekhoa ea ho ja, 'me e na le kamohelo e phahameng ea lijo. Ntle le moo, li-coupsules tsa HPMC tse nang le li-HPMC li boetse li na le thepa e latelang e ikhethang:
Likahare tsa metsi a tlase - hoo e ka bang 60% e tlase ho isa ho gelatin e sa lefelloeng
Litaba tsa metsi tsa Gelatin Hollow ka kakaretso li na le lilemo tse 12.5% -17.5%. Mocheso le mongobo oa tikoloho o lokela ho laoloa nakong ea mofuta o loketseng nakong ea tlhahiso, lipalangoang, tšebeliso ea li-capsules se se nang thuso. Mocheso o loketseng o 15-25 ° C le Mongobo o lekanang ke 35% -65%, e le hore ts'ebetso ea sehlahisoa e ka bolokoa nako e telele. Taelo ea metsi a fipm ea HPMC e tlase haholo, ka kakaretso 4% -5%, e ka bang 60% e tlase ho 60% e ka tlase ho 60% e tlase. Phapanyetsano ea metsi le tikoloho ea polokelo ea nako e telele e tla eketsa litaba tsa metsi a sets'oants'o sa HPMC liphutheloana tse boletsoeng, empa e ke ke ea feta
Nako ea poso: Jun-07-2023