Hydroxypropypropypropinyl Methylcelll. HPMC e na le polokeho e ntle ea metsi, e phallang, e theha thepa le tsitsipano ea lifilimi, 'me thepa ea botsitso le tsitsipano ea eona e na le litlamorao tse kholo ho boloka metsi.
1. Melao-motheo ea Matla a HpMC ea Metsi a Hlajoa
HPMC e theha sebopeho sa netweke ea likarolo tse tharo ka ho kenya letsoho le ho tsekisana le 'mele ka tharollo ea molek'hule, e ka tšoarelang ka katleho le ho boloka mongobo. Ho boloka metsi ho bonahala haholo likarolo tse latelang:
K'hono ea 'mele: Lihlopha tsa hydroyl li ka sengoathoana sa balecular li ka baka limoleke tsa metsi, a sebelisa limolek'hule tsa metsi, le ho monya mongobo.
Phekolo ea liketsahalo: HPMC e eketsa pono ea tharollo mme e fokotsa ho pharalla ha metsi, ka ho etsa joalo, a fokotsa mouoane le ho kenella ha metsi.
Ho theha filimi ho theha: HPMC e ka theha filimi e sirelletsang ea Uniform ho thibela mouoane oa mongobo.
2. Phello ea ho tsepamisa maikutlo ho bolokolohi ba metsi ho HPMC
Ts'ebetso ea ho boloka metsi ho boloka metsi a HPMC e amana haufi le ho tsepamisa maikutlo ka tharollo, 'me litlamorao tsa bolulo tse fapaneng li bontšoa menyakeng e fapaneng.
2.1 LITLHAKISO TSE KHOLO
Ka har'a metsero e tlase (hangata e ka tlase 0,1%), limolek'hule tsa HPMC ha li thehe marang-rang a likarolo li tharo metsing. Le ha ho na le bokhoni bo itseng ba metsi le phello ea meno, ho boloka metsi ho sebelisoa ka lebaka la tšebelisano-'moho e fokolang ea ho apa. Ka nako ena, ho boloka metsi tharollo ho latela bokhoni ba ho ala ha limolek'hule.
2.2 Masimo a Kopaneng a Mekhabiso
Ha leqhubu la HPMC le eketseha pakeng tsa 0,1% le 2%, sebopeho sa marang-rang se tsitsitseng se thehoa. Ka nako ena, ke pono ea tharollo e eketseha haholo, e eketsa bokhoni ba metsi le ts'ebetso ea metsi ea ho boloka metsi. Limolek'hule tsa HPMC li theha marang-rang a litopo ka ho le hokela 'meleng, ka katleho ho fokotsa phallo le ho theola metsi a mangata. Ka hona, ho bolokoa ka metsing ka HPMC ho ntlafatsoa haholo libakeng tse mahareng.
2.3 Boleng bo phahameng ba mahloriso
Ka libaka tse phahameng (hangata tse kholo ho feta 2%), limolek'hule tsa HPMC li theha sebopeho sa marang-rang se tetemang, mme tharollo e bonts'a boemo bo phahameng ba gel. Boemong bona, HPMC e khona ho hapa le ho boloka mongobo ho isa tekanyong e kholo ka ho fetisisa khetlong e ka khonehang. Ho tsepamisa likelello tsa HPM haholo ho eketsa bophahamo ba metsi a metsi, ho li thibela ho thibela ts'ebetso e ntle ea ho boloka likopo tse hlokang ho boloka metsi a mangata.
3. Sesebelisoa se sebetsang sa HPMC ho boloka metsi le ho boloka metsi
3.1 Lebaka la kaho
Ho tlosa seretse, HPMC e ntlafatsa ts'ebetso ea kaho ka ho ntlafatsa ho boloka metsing, ho fokotsa metsi nakong ea ho qala, ho eketsa nako ea ho qala. HPMC e sebelisoa ka linako tse ling e nang le li-instar tsa 0,1% ho 1.0% ho 1.0%, mofuta o lekanyang polokeho ea metsi le pono ea kopo.
3.2 Tšimo ea pharmaceutical
Litotleng tsa meriana, HPMC e sebelisoa e le thepa e tolokiloeng le e 'ngoe ea tokollo ho fihlela litlamorao tse kholo tsa lithethefatsi ka ho jala sekhahla sa ho lokolla. Khatello ea HPMC ho meriana hangata e tloha ho 1% ho isa ho 5%, e fanang ka bolokolohi ba metsi le tokollo ea lithethefatsi ho tloha letlapeng.
3.3 tšimo ea lijo
Indastering ea lijo, HPMC e sebelisoa e le tlhekenener le ba hlolloang ho ntlafatsa sebopeho le lihlahisoa tsa metsi tsa lihlahisoa. Mohlala, eketsa HPMC ho bohobe bo ka ntlafatsa ho boloka metsi le bofoko ba hlama, hangata ho ba le hlama lipakeng tsa 0,2% le 1%.
4. Kholiseho ea ho boloka metsi ke HPMC khatello ea mahloriso
Ho ntlafatsa khatello ea maikutlo ea HPMC bakeng sa ho boloka metsi ho itlhoekisa ka metsing e hloka ho nahanisisa ka mekhoa e meng ea ts'ebetso ntle le thepa ea ho lokisa le thepa e 'ngoe ea tharollo.
Khatello ea HPMC e na le phello e bohlokoa ho boloka metsi ka tharollo. Ka meaho e tlase, bolokolohi ba metsi bo na le meeli; Mangakeng a Mendium, ho thehiloe sebopeho se tsitsitseng ho ntlafatsa ho bolokoa metsing; Ka meaho e phahameng, phello ea ho boloka metsi e ngata ea metsi e fihletsoe. Masimo a fapaneng a kopo a na le litlhoko tse fapaneng bakeng sa khatello ea HPMC
Poso: Hlakubele-17-2025